Friday, November 13, 2009

How personalized should medicine be?

IT and Medicine/Medical IT

If you have a complete health record and access to your own medical records, you can put together your own health & medical record for your doctors to see each time you go to see one for some ailment.

Whether doctors should know a patient's health & medical history before they treat a patient is entirely up to them. They can choose to ignore whatever knowledge and evidence you bring to them. They are under no obligation to accept what you wish them to know about you before they treat your present ailment unless they choose to. Since there is no compulsion to know everything about a patient, you stand to lose.

Should doctors take note of what patients are about to inform them about their own ailments? Are doctors prepared to handle what their patients are willing to tell them or share anything about their ailments? Are patients more informed about their ailments compared to the 80s?

Patients today are more drawn into gathering information about their health and ailments in order to understand what they are suffering from and the various forms of treatment available. Patients are coming to doctors when they are fully informed. Are doctors prepared to give patients personalized medicine, fully knowing that it is what patients want and why they are seeing doctors in the first place?

Read about why Ester Dyson chose to have her health data online:

Do doctors have access to tools that can help them understand how to go about prescribing fast and safe personalized medicine?

Keywords:
telehealth, telemedicine, bioinformatics, medical informatics, health informatics, genomics, proteomics, genotype, phenotype, karyotype, polymorphism, multi-factorial

Disease Information:
Centers for Disease Control and Prevention (CDC, Atlanta, Georgia, USA)

CDC data and survey systems:

Gene & protein databases:
OMIM = Online Mendelian Inheritance in Man

Medical citation templates:
OMIM - Wikipedia

Bioinformatics software

Medical external link templates:

Journal databases:
PubMed
OVID
Cochrane Library

WEAT: Web Enabled Analysis Tool
The BRFSS, the world’s largest telephone survey, tracks health risks in the United States. Information from the survey is used to improve the health of the American people.

Asthma data

Cholesterol data

Cancer Informatics

BRCA1; Breast cancer 1, early onset

Location: 17q21

Overview: BRCA1 is a breast cancer susceptibility gene that was first identified in 1994. People carrying a mutation (abnormality) in this gene are at an increased risk of breast or ovarian cancer. The normal gene plays a role in repairing breaks in DNA. However, when the gene is mutated it is thought that this repair function may become disabled thus leading to more DNA replication errors and cancerous growth

OMIM
GeneCard (Weizmann Institute)
Human Gene Mutation Database (Cardiff, UK)
Tumor Gene Database
Swiss-Prot
Locus Link
UniGene
GenAtlas
GDB
Nomenclature (search for BRCA1)

Breast Cancer and the BRCA1 Gene (NCI, NIH)
BRCA1 and BRCA2 Hereditary Breast Cancer (University of Washington) part of the NCI funded Geneclinics.org site. Details of BRCA1 and BRCA2 breast cancer, risk assessment, diagnosis, management, molecular biology, genetic counseling, resources, references etc
BRCA1 / BRCA2 in Breast and Ovarian Cancer (National Center for Biotechnology Information) an overview of the BRCA1 and BRCA2 genes with links to other gene databases.
CancerGene - computer program (University of Texas / Duke University) for health professionals: a computer program for estimating the likelihood that a family carries a mutation in one of the cancer predisposition genes BRCA1, BRCA2, MSH2 or MLH1
Breast Cancer Resources
Ovarian Cancer Resources
BRCA2 gene (13q12.3)

  • Medline Search: BRCA1 (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews]
    Search Medline for related articles (PubMed)
  • Medline Search: cancer AND gene AND BRCA1[TI] (PubMed) Limit search to: [Last Year] Limit search to: [Last 2 Years] Limit search to: [Reviews]
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